Resources

RCL highlights some important papers in the field of hyperthermia.

Dispersion-retention-formulation Method Paper
P. Southern and Q. A. Pankhurst JMMM 2018 (pre-print)
Using the ‘dispersion-retention-formulation method’ to estimate clinical and preclinical dosage limits for interstitial nanomedicines or agents

Dispersion-retention-formulation Excel calculator
‘Dispersion-retention-formulation method’ Excel calculator.

Commentary on the clinical and preclinical dosage limits of interstitially administered magnetic fluids for therapeutic hyperthermia based on current practice and efficacy models
P. Southern and Q. A. Pankhurst International Journal of Hyperthermia, vol. 1, pp. 1–16, Oct. 2017
Commentary on the clinical and preclinical dosage limits of interstitially administered magnetic fluids for therapeutic hyperthermia based on current practice and efficacy models.

On the reliable measurement of specific absorption rates and intrinsic loss parameters in magnetic hyperthermia materials
Wildeboer, R. R., Southern, P., Pankhurst, Q.
Journal of Physics D: Applied Physics (2014), 47(49), 495003. doi:10.1088/0022-3727/47/49/495003

This paper demonstrates the importance of standardising a measurement protocol for determining the SAR & ILP in a non-adiabatic system. MATLAB and Excel scripts can freely be downloaded for personal, academic and commercial from the downloads section. Instructions for the MATLAB script are included in the download.

A low cost synthesis method for functionalised iron oxide nanoparticles for magnetic hyperthermia from readily available materials
Bear, J. C., Bin Yu, Blanco-Andujar, C., McNaughter, P. D., Southern, P., Mafina, M.-K., et al.
Faraday Discussions (2014), 00, 1–13. doi:10.1039/C4FD00062E

An interesting paper promoting an alternative approach to synthesising hyperthermia agents using materials available on the high street.

Magnetic Hyperthermia In Nanoscience
Ortega, D., & Pankhurst, Q. A.
Magnetic hyperthermia In Nanoscience (Vol. 1, pp. 60–88). Cambridge: Royal Society of Chemistry (2012). doi:10.1039/9781849734844-00060

A chapter from this periodical review summarising some of the technologies and results RCL have been engaged in.

Suitability of commercial colloids for magnetic hyperthermia
Kallumadil, M., Tada, M., Nakagawa, T., Abe, M., Southern, P., & Pankhurst, Q. A.
Journal of Magnetism and Magnetic Materials 2009, 321(10), 1509–1513. doi:10.1016/j.jmmm.2009.02.075

This paper discusses a new parameter to govern the effectiveness of a hyperthermia agent. The Specific Absorption Rate (SAR) is typically used in the literature, however this is system dependent and doesn’t take into account the strength and frequency of the magnetic field. The authors present a new metric, called the Intrinsic Loss Power (ILP), that provides a more comparable parameter to quote when comparing the effectiveness of hyperthermia agents.

BBC London News Report

Tumours could be ‘cooked’ with magnetic particles
The Times wrote a short article in October 2009 about a project UCL was involved involving magnetic hyperthermia.
times article oct09